In cases where the man produces very few sperm or when the sperm movement is poor and in cases where the sperm is obtained directly from the testes Intra Cytoplasmic Sperm Injection (ICSI) technique is used. This is because such sperm is usually incapable of fertilizing the egg unassisted.

Women are advised to use these hormone medications after eggs have been collected to help prepare the womb lining for the implantation of the embryo. We recommend you use them for two weeks at least because the pituitary gland suppression drugs mentioned above may cause natural progesterone hormone level to drop.